The Dialysis and Transplant Registry was established by the Department of Nephrology, Kuala Lumpur Hospital (HKL) in 1992 to collect data from patients on renal replacement therapy within the Ministry of Health (MOH). In order to expand coverage to include non-MOH patients so that the registry may truly claim to be a national one, the ownership was transferred to the Malaysian Society of Nephrology. It was subsequently named Malaysian Dialysis and Transplant Registry (MDTR). MDTR collects information on patients with end stage renal disease (ESRD) on renal replacement therapy (RRT) in Malaysia.

This was subsequently renamed the National Renal Registry as its scope expanded and currently provide a national database for deceased donor kidney allocation (eMOSS) and collect data for the Malaysian Registry of Renal Biopsy (MRRB). Future undertakings will include the Living Kidney Donor Registry and the Interventional Nephrology Registry.

In 2017, NRR has upgraded the data collection processes from a paper based to a web-based system and is called eNRR. The eNRR is more efficient and will enable SDPs the ability to access and tabulate their data on line.